Services

What We Do

Toprion Bio provides integrated preclinical research services to support drug discovery and early development programs across multiple therapeutic areas.

Our capabilities span animal model development, in vivo pharmacology, pharmacokinetics, toxicology, pathology, and translational research support — helping clients generate reliable data for preclinical decision-making.

We work with biotechnology companies, pharmaceutical partners, and academic research teams to design and execute studies tailored to specific scientific objectives, development stages, and program timelines.

Our service areas include:

  • In Vivo Pharmacology & Efficacy Studies
  • Animal Disease Models
  • Pharmacokinetics (PK) & Early ADME
  • Safety & Toxicology Evaluation
  • Pathology & Biomarker Analysis
  • Integrated Preclinical Study Support

With broad model coverage, responsive project coordination, and flexible study execution, we support programs ranging from early proof-of-concept to IND-enabling research.

Our team focuses on delivering high-quality preclinical data with efficient communication, operational flexibility, and scientifically aligned study strategies.

Chemical Research

Medicinal Chemistry
Synthetic Chemistry
Chemical Analysis
Early Process Chemistry

Biological Sciences

Drug Screening
In Vitro Biology
In Vivo Pharmacology
In Vitro Disease Biology
Structural Biology
Computational Biology and Molecular Modeling

Drug Safety Evaluation

General Toxicology
Safety Pharmacology
Genetic Toxicology
Ophthalmic Toxicology
Clinical Pathology
Toxicokinetics
Immunotoxicity
Reproductive Toxicology
Pathology Research
Bioanalytical Services

Pharmacokinetics

In Vitro ADME Studies
In Vivo ADME Studies
PK/PD Studies

Clinical Services

Clinical Trial Application
Clinical Research

Drug Modalities We Support

Small Molecules

Lead optimization
PK/PD
Dose finding
Mechanism studies

Biologics

Monoclonal antibodies
Bispecific antibodies
ADC
Fusion proteins

Cell Therapy

CAR-T / CAR-NK
Stem cell therapy
TIL / TCR-T
Exosome

Gene Therapy

AAV
Gene editing (CRISPR)
Lentivirus
Plasmid DNA

RNA Therapeutics

mRNA
siRNA
ASO
RNA-LNP

Medical Devices

Implantable devices
Combination products
Safety evaluation

How We Work

1. Scientific Discussion

Understand your research goals, target indication and project constraints

2. Feasibility Assessment

Evaluate animal models, study endpoints and feasible technical approaches
Within 1 Business Day

3. Study Design

Customize trial protocol, define endpoints, sample quantity & project timeline

4. Quotation

Provide transparent service scope and clear pricing details

5. Project Kick-off

Finalize full study plan and officially launch your research project

6. Study Execution

Carry out high-standard trials and complete full data collection

7. Data Review

Conduct professional data analysis and scientific result interpretation

8. Final Report

Deliver a comprehensive research report & outline follow-up development suggestions