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Expert Q&A: Improving the Quality and Reproducibility of In Vivo Studies
In Vivo StudiWell-designed animal studies require more than selecting an appropriate disease model. Experimental grouping, endpoint selection, procedural consistency, and…
Industry Insight——Building a Stronger IND Strategy for Small Molecule Drug Development
Bringing a small molecule from discovery to clinical development is a complex process that requires far more than identifying a…
Technical Insight——Hyperthyroid Heart Disease: Modeling Strategy and Translational Evaluation
Hyperthyroid heart disease (HHD) represents one of the most severe cardiovascular complications of thyroid hormone excess. Clinically, it is characterized…
Technical Insight——Why Organoids Are Becoming a Critical Tool in Drug Discovery
For decades, preclinical research has relied heavily on two experimental systems: traditional cell cultures and animal models. Both have contributed…
Technical Insight——Why Targeted Protein Degradation Is Reshaping Drug Discovery
For decades, drug discovery has largely relied on inhibition. Whether targeting kinases, receptors, or enzymes, most therapeutic strategies have focused…
Technical Insight——Why Hyperuricemia Models Often Produce Unstable Results
Hyperuricemia (HUA) research has expanded far beyond gout alone. Elevated uric acid levels are now closely associated with chronic kidney…