Muridda provides customers with professional services including chiral separation, high-throughput purification, physicochemical property determination, and impurity isolation and identification. We deliver high-quality comprehensive analytical services in a rapid and cost-effective manner, providing accurate, high-quality data at reasonable prices to support compound library, medicinal chemistry, synthetic chemistry, discovery chemistry, and process chemistry programs.
Analytical and Purification Services
- Analytical method development for chiral separation
- Chiral separation from milligram scale to several kilogram scale
- Large-scale (up to hundreds of kilograms) chiral and achiral separation
- Achiral SFC purification and crude sample purification
- High-throughput quality control and purification of library compounds (including DNA-encoded libraries)
- Compound characterization and reference material characterization
- Method development for genotoxic impurities
- Ion analysis via IC
- Method development and analysis for metals via ICP-OES and ICP-MS
- Structural confirmation studies using HR-MS, LC-MS/MS, IR, UV, and elemental analysis
- Impurity structure elucidation studies
- NMR and Q-NMR services for structural elucidation of isolated impurities through acquisition and interpretation of comprehensive 1D/2D NMR data
- Regulatory-driven analytical services for pharmaceutical development, including monitoring and quality control of APIs, intermediates, raw materials, and finished products
- Isolation and structural elucidation of impurities in APIs and pharmaceutical products
- Physicochemical property determination (pKa, LogP/LogD, solubility, and concentration)
- Extraction, isolation, and structural elucidation of natural products
- Small molecule screening via high-affinity selection mass spectrometry (ASMS)