PK/PD studies utilize analytical methods to determine the distribution levels of test compounds and biomarkers in the circulatory system and various tissues, especially target organs, in normal or disease model animals, thereby establishing the correlation between drug metabolism and pharmacological response.
In vivo PK and PD studies enable our clients to balance efficacy and potential toxicity of their drug candidates at an early stage, thus reducing the risk of clinical failure.
Muridda provides disease model establishment and animal model studies, as well as quantitative biological detection of biomarkers.
Service Items
- Concentration of test compounds in blood circulation
- Distribution of test compounds in tissues and target organs
- Distribution of specific biomarkers in blood and tissues