Under the NHP Shortage, This Study Design Could Save Millions A biotech company’s ADC program was about to enter IND-enabling safety assessment when the team was informed that the next available cynomolgus monkey study slot was more than six months away, with the cost approaching RMB 200,000 per animal. The timing of the company’s financing, […]
Case Study——Smarter Study Design Amid the NHP Shortage Read More »
Study Focus Natural Killer (NK) cell biology and translational model support for immunotherapy development, including functional assays, disease modeling, and evaluation of NK-targeted therapeutic strategies. Background NK cells are innate lymphocytes responsible for rapid elimination of tumor and virus-infected cells without prior sensitization. Their activity is governed by a balance between inhibitory receptors (e.g., KIR,
Project Background A research team conducting studies in aging ischemic stroke sought an integrated workflow covering in vitro cellular assays, animal models, and tissue-level validation to evaluate ischemia-reperfusion injury-associated cellular dysfunction and tissue abnormalities. Due to the multi-level pathology of ischemic stroke, the project required coordinated execution across: Additionally, cell stability, animal model timelines, and
Project Background A research team conducting studies in post-infectious irritable bowel syndrome (PI-IBS) required a stable, reproducible, and translationally relevant preclinical workflow to evaluate disease-associated intestinal dysfunction and visceral hypersensitivity phenotypes. As a multifactorial gastrointestinal disorder, PI-IBS research often involves the integration of infection-related induction, chronic stress exposure, behavioral assessment, and tissue-level evaluation. As a
Project Background A research team conducting intervertebral disc degeneration studies required an integrated workflow covering clinical samples, primary cell-based studies, and in vivo validation to evaluate degeneration-associated inflammatory responses, cellular dysfunction, and tissue-level changes. Because intervertebral disc degeneration involves complex multi-level pathological processes, the project required coordinated execution across: In addition, primary cell stability, long
To elucidate the pathogenesis of MS and EAE, and to provide a basis for disease monitoring, relapse prevention, and the selection of therapeutic strategies.
To elucidate the pathogenesis of MS and EAE, and to provide a basis for disease monitoring, relapse prevention, and the selection of therapeutic strategies.
