How do I choose between ELISA and multiplex bead assays (CBA) for cytokine release testing?
Choose ELISA when measuring a single, well-defined cytokine that requires standardized dynamic range and direct historical benchmarking. Choose multiplex bead assays (such as cytometric bead array, CBA) when profiling multiple cytokines simultaneously from volume-constrained in vitro supernatants or biofluid samples. Your selection depends on sample volume availability, target panel breadth, cross-reactivity risk, and throughput requirements. […]